# Histamine Receptor Antagonists --- **Histamine-2 receptor antagonists** (sometimes called **H2 blockers**) are a class of [[medicine]] that work as [[peptic ulcer disease|antiulcer]] agents. They decrease [[stomach acid|gastric acid]] production, which allows for the healing an prevention of [[peptic ulcer disease|peptic ulcers]] as well as improve the effects of [[GERD]]. ## Contraindications Use cautiously for renal impairment. ## Adverse Reactions The most common side effect is confusion. ## Examples - **Famotidine** (brand name: **Pepcid**) ___